Medications · Dermatology

Compounded Topical Anesthetics (BLT, LET)

Custom topical anesthetic combinations for procedural use.

What it does

What Compounded Topical Anesthetics (BLT, LET) is and why doctors prescribe it.

BLT (benzocaine, lidocaine, tetracaine) and LET (lidocaine, epinephrine, tetracaine) are compounded topical anesthetic combinations prescribed by doctors for procedural anesthesia — minor dermatologic procedures, laser treatments, micro-needling, and select pediatric uses.

How it works

Mechanism in plain English.

Each component is a local anesthetic that blocks voltage-gated sodium channels in sensory nerve endings. The combination provides faster onset and broader coverage than any single agent alone. Strengths are calibrated for topical (not injectable) use.

How long it's been studied

Research history.

Topical anesthetic compounding has been used for decades in dermatology and minor procedure contexts. Compounded BLT and LET are dispensed under 503A on doctor prescription.

Dosing

Clinical context for the prescribing doctor.

Doctor-prescribed. Compounded BLT typically combines 20% benzocaine, 6% lidocaine, and 4% tetracaine; LET combines 4% lidocaine, 1:1000 epinephrine, and 0.5% tetracaine. Applied 30–60 minutes before procedure under occlusion. Your prescribing doctor selects formulation and application protocol.

This page is informational, not a dispensing aid. Compounded Topical Anesthetics (BLT, LET) is dispensed only on a patient-specific prescription written by a licensed doctor for an identified patient. Compounded drugs are not FDA-approved and should not be evaluated using branded-drug trial data. Availability varies by state and prescribed medication.

How to access Compounded Topical Anesthetics (BLT, LET) through RonanRx

Three paths.

Doctors can prescribe compounded Compounded Topical Anesthetics (BLT, LET) for individual patients through RonanRx. Patients with a doctor can sign up to receive their prescription. Patients without a doctor can learn how the referral works.

For doctors

Request a partnership call.

A pharmacist will follow up within two business days. We'll cover state availability, supported formulations, and what integration looks like for your clinic.

Request partnership call →

Patient with a doctor

Sign up to receive your prescription.

If your doctor has already prescribed Compounded Topical Anesthetics (BLT, LET), sign up so we can prepare and ship your medication. The signup wizard collects intake and connects you to the prescribing workflow.

Sign up →

Patient without a doctor

Get referred by a partner clinic.

RonanRx prescribes through partner clinics — we don't initiate prescriptions on this site. Read how the referral process works and how to find a partner clinic in your state.

For patients →

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