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Medications · Hormone optimization
Progesterone
Bioidentical progesterone for HRT and gynecologic care.
What it does
What Progesterone is and why doctors prescribe it.
Progesterone is the steroid hormone produced by the corpus luteum during the second half of the menstrual cycle and by the placenta in pregnancy. In compounded HRT it's prescribed alongside estrogen to oppose estrogen's effect on the endometrium, and standalone for cyclical and luteal-phase support, sleep difficulties associated with low progesterone, and select fertility-adjacent indications the prescribing doctor identifies.
How it works
Mechanism in plain English.
Bioidentical progesterone binds the progesterone receptor and produces effects that distinguish it from synthetic progestins (the molecules in many manufactured oral contraceptives). Compounded progesterone is dispensed in oral capsules, sublingual troches, topical creams, and vaginal suppositories — letting the prescribing doctor match dose form to clinical need.
How long it's been studied
Research history.
Progesterone was first isolated in 1934 and chemically characterized shortly after. Decades of clinical research distinguish bioidentical progesterone from synthetic progestins. In modern HRT, the PEPI trial (1995), KEEPS trial (2014), and ongoing observational cohorts have informed how compounded bioidentical progesterone is prescribed.
Dosing
Clinical context for the prescribing doctor.
Doctor-prescribed. Oral progesterone for HRT is commonly used in the 100–200 mg nightly range; topical creams use a different strength schedule; vaginal preparations are dosed locally. Your doctor selects the route and dose based on cycle phase, symptom pattern, and concurrent estrogen therapy. RonanRx compounds each prescription to specification.
This page is informational, not a dispensing aid. Progesterone is dispensed only on a patient-specific prescription written by a licensed doctor for an identified patient. Compounded drugs are not FDA-approved and should not be evaluated using branded-drug trial data. Availability varies by state and prescribed medication.
How to access Progesterone through RonanRx
Three paths.
Doctors can prescribe compounded Progesterone for individual patients through RonanRx. Patients with a doctor can sign up to receive their prescription. Patients without a doctor can learn how the referral works.
Patient with a doctor
Sign up to receive your prescription.
If your doctor has already prescribed Progesterone, sign up so we can prepare and ship your medication. The signup wizard collects intake and connects you to the prescribing workflow.
Patient without a doctor
Get referred by a partner clinic.
RonanRx prescribes through partner clinics — we don't initiate prescriptions on this site. Read how the referral process works and how to find a partner clinic in your state.