Peptides · Tissue repair (under FDA review)

KPV

Tripeptide derivative of α-MSH with anti-inflammatory research.

What it does

What KPV is and why doctors prescribe it.

KPV is a tripeptide (lysine-proline-valine) derived from the C-terminal of alpha-melanocyte-stimulating hormone (α-MSH). Research focus is on its anti-inflammatory properties, particularly in mucosal and dermal contexts. Under FDA review for 503A access.

How it works

Mechanism in plain English.

α-MSH itself has well-characterized anti-inflammatory effects via melanocortin receptor signaling. KPV captures a fragment of that activity and may also act through receptor-independent intracellular pathways. Research has examined applications in inflammatory bowel conditions and skin inflammation.

How long it's been studied

Research history.

KPV has been studied since the 1980s as part of α-MSH peptide-fragment research. Preclinical and small clinical work has examined its activity in IBD models and inflammatory skin conditions. Cannot currently be compounded under 503A.

Dosing

Clinical context for the prescribing doctor.

Pending regulatory clarity. RonanRx cannot compound KPV until it receives 503A-permissible status.

This page is informational, not a dispensing aid. KPV is dispensed only on a patient-specific prescription written by a licensed doctor for an identified patient. Compounded drugs are not FDA-approved and should not be evaluated using branded-drug trial data. Availability varies by state and prescribed medication.

How to access KPV through RonanRx

Three paths.

KPV is currently in Category 2 and not available for 503A compounding. RonanRx is tracking the FDA review and will notify partner clinics when the decision allows compounding access.

For doctors

Request a partnership call.

A pharmacist will follow up within two business days. We'll cover state availability, supported formulations, and what integration looks like for your clinic.

Request partnership call →

Patient with a doctor

Sign up to receive your prescription.

If your doctor has already prescribed KPV, sign up so we can prepare and ship your medication. The signup wizard collects intake and connects you to the prescribing workflow.

Sign up →

Patient without a doctor

Get referred by a partner clinic.

RonanRx prescribes through partner clinics — we don't initiate prescriptions on this site. Read how the referral process works and how to find a partner clinic in your state.

For patients →

Related

Related substances at RonanRx