Peptides · Neuro & cognitive (under FDA review)

Semax

Neurotrophic / cognitive peptide.

What it does

What Semax is and why doctors prescribe it.

Semax is a synthetic peptide based on a fragment of ACTH (4-10) with modifications for stability. Research focus is on neurotrophic effects, cognitive enhancement, and recovery after stroke. Approved in Russia for stroke recovery; under FDA review in the U.S.

How it works

Mechanism in plain English.

Semax has been reported to upregulate BDNF (brain-derived neurotrophic factor) and NGF (nerve growth factor) expression, with downstream effects on neuroplasticity. Clinical studies in Russia have examined applications in ischemic stroke, optic nerve disorders, and ADHD.

How long it's been studied

Research history.

Semax was developed by Russian researchers in the 1980s-90s. Clinical evidence is largely from Russia and includes use in stroke recovery as an approved therapy there. Cannot currently be compounded under 503A in the U.S.

Dosing

Clinical context for the prescribing doctor.

Pending regulatory clarity.

This page is informational, not a dispensing aid. Semax is dispensed only on a patient-specific prescription written by a licensed doctor for an identified patient. Compounded drugs are not FDA-approved and should not be evaluated using branded-drug trial data. Availability varies by state and prescribed medication.

How to access Semax through RonanRx

Three paths.

Semax is currently in Category 2 and not available for 503A compounding. RonanRx is tracking the FDA review and will notify partner clinics when the decision allows compounding access.

For doctors

Request a partnership call.

A pharmacist will follow up within two business days. We'll cover state availability, supported formulations, and what integration looks like for your clinic.

Request partnership call →

Patient with a doctor

Sign up to receive your prescription.

If your doctor has already prescribed Semax, sign up so we can prepare and ship your medication. The signup wizard collects intake and connects you to the prescribing workflow.

Sign up →

Patient without a doctor

Get referred by a partner clinic.

RonanRx prescribes through partner clinics — we don't initiate prescriptions on this site. Read how the referral process works and how to find a partner clinic in your state.

For patients →