Peptides · Neuro & cognitive (under FDA review)

Vasoactive Intestinal Peptide (VIP)

Endogenous neuropeptide with broad signaling roles.

What it does

What Vasoactive Intestinal Peptide (VIP) is and why doctors prescribe it.

VIP is an endogenous 28-amino-acid neuropeptide with widespread distribution in the gut and central nervous system. Research interest spans circadian biology, immune modulation, vasodilation, and respiratory applications (intranasal VIP has been studied in chronic inflammatory conditions). Under FDA review for compounding access.

How it works

Mechanism in plain English.

VIP binds VPAC1 and VPAC2 receptors with broad effects: vasodilation, smooth-muscle relaxation, modulation of inflammatory cytokine production, and effects on the suprachiasmatic nucleus circadian clock. Different routes of administration (intranasal vs systemic) target different application areas.

How long it's been studied

Research history.

VIP was discovered in 1970 by Said and Mutt. Decades of basic and translational research inform its biology. Cannot currently be compounded under 503A.

Dosing

Clinical context for the prescribing doctor.

Pending regulatory clarity.

This page is informational, not a dispensing aid. Vasoactive Intestinal Peptide (VIP) is dispensed only on a patient-specific prescription written by a licensed doctor for an identified patient. Compounded drugs are not FDA-approved and should not be evaluated using branded-drug trial data. Availability varies by state and prescribed medication.

How to access Vasoactive Intestinal Peptide (VIP) through RonanRx

Three paths.

Vasoactive Intestinal Peptide (VIP) is currently in Category 2 and not available for 503A compounding. RonanRx is tracking the FDA review and will notify partner clinics when the decision allows compounding access.

For doctors

Request a partnership call.

A pharmacist will follow up within two business days. We'll cover state availability, supported formulations, and what integration looks like for your clinic.

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Patient with a doctor

Sign up to receive your prescription.

If your doctor has already prescribed Vasoactive Intestinal Peptide (VIP), sign up so we can prepare and ship your medication. The signup wizard collects intake and connects you to the prescribing workflow.

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Patient without a doctor

Get referred by a partner clinic.

RonanRx prescribes through partner clinics — we don't initiate prescriptions on this site. Read how the referral process works and how to find a partner clinic in your state.

For patients →

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