Peptides · Neuro & cognitive (under FDA review)

DSIP — Delta Sleep-Inducing Peptide

Sleep-related nonapeptide.

What it does

What DSIP — Delta Sleep-Inducing Peptide is and why doctors prescribe it.

DSIP (Delta Sleep-Inducing Peptide) is a nonapeptide originally isolated from rabbit cerebral venous blood during EEG-defined slow-wave sleep. Research interest spans sleep architecture, stress response, and select neurological applications. Under FDA review.

How it works

Mechanism in plain English.

DSIP's exact mechanism is incompletely characterized. Effects on slow-wave sleep, stress-axis modulation (cortisol, ACTH), and possible mu-opioid system interactions have all been reported, with the strongest data in the sleep and stress contexts.

How long it's been studied

Research history.

DSIP was first isolated and characterized in 1977. Research interest peaked in the 1980s-90s and has continued at lower volume. Cannot currently be compounded under 503A.

Dosing

Clinical context for the prescribing doctor.

Pending regulatory clarity.

This page is informational, not a dispensing aid. DSIP — Delta Sleep-Inducing Peptide is dispensed only on a patient-specific prescription written by a licensed doctor for an identified patient. Compounded drugs are not FDA-approved and should not be evaluated using branded-drug trial data. Availability varies by state and prescribed medication.

How to access DSIP — Delta Sleep-Inducing Peptide through RonanRx

Three paths.

DSIP — Delta Sleep-Inducing Peptide is currently in Category 2 and not available for 503A compounding. RonanRx is tracking the FDA review and will notify partner clinics when the decision allows compounding access.

For doctors

Request a partnership call.

A pharmacist will follow up within two business days. We'll cover state availability, supported formulations, and what integration looks like for your clinic.

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Patient with a doctor

Sign up to receive your prescription.

If your doctor has already prescribed DSIP — Delta Sleep-Inducing Peptide, sign up so we can prepare and ship your medication. The signup wizard collects intake and connects you to the prescribing workflow.

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Patient without a doctor

Get referred by a partner clinic.

RonanRx prescribes through partner clinics — we don't initiate prescriptions on this site. Read how the referral process works and how to find a partner clinic in your state.

For patients →