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Peptides · Available now
Sermorelin
GHRH analog with longstanding 503A history.
What it does
What Sermorelin is and why doctors prescribe it.
Sermorelin is a synthetic analog of growth hormone-releasing hormone (GHRH), comprising the first 29 amino acids of endogenous GHRH (the active sequence). It's one of the few growth-hormone-axis peptides with a long 503A compounding history. Doctors prescribe it for adult growth-hormone-axis support in select clinical contexts.
How it works
Mechanism in plain English.
Sermorelin binds the GHRH receptor on pituitary somatotrophs, stimulating endogenous growth hormone release. Unlike administering recombinant human growth hormone (which provides exogenous GH), sermorelin works through the body's own pulsatile GH release machinery, which preserves negative feedback and tends to maintain a more physiologic profile.
How long it's been studied
Research history.
Sermorelin was developed in the 1970s and approved by the FDA in 1997 (under the brand Geref) for pediatric growth hormone deficiency. Adult off-label and compounded use in growth-hormone-axis support has accumulated decades of clinical experience.
Dosing
Clinical context for the prescribing doctor.
Doctor-prescribed. Compounded sermorelin is typically dispensed at strengths around 3 mg/vial for subcutaneous administration before sleep, when endogenous GH release is naturally peaking. Your doctor selects dose and frequency based on the patient's clinical picture.
This page is informational, not a dispensing aid. Sermorelin is dispensed only on a patient-specific prescription written by a licensed doctor for an identified patient. Compounded drugs are not FDA-approved and should not be evaluated using branded-drug trial data. Availability varies by state and prescribed medication.
How to access Sermorelin through RonanRx
Three paths.
Doctors can prescribe compounded Sermorelin for individual patients through RonanRx. Patients with a doctor can sign up to receive their prescription. Patients without a doctor can learn how the referral works.
Patient with a doctor
Sign up to receive your prescription.
If your doctor has already prescribed Sermorelin, sign up so we can prepare and ship your medication. The signup wizard collects intake and connects you to the prescribing workflow.
Patient without a doctor
Get referred by a partner clinic.
RonanRx prescribes through partner clinics — we don't initiate prescriptions on this site. Read how the referral process works and how to find a partner clinic in your state.